IGF-1 LR3

What is IGF-1 LR3?

IGF-1 LR3, or insulin-like growth factor-1 long arginine 3, is a synthetic variant of insulin-like growth factor-1 (IGF-1) specifically engineered for prolonged activity. This modified peptide boasts a remarkably extended half-life, lasting up to 120 times longer than standard IGF-1, primarily due to its decreased binding affinity to IGF-1 binding proteins. This extended presence in the bloodstream enhances its therapeutic effectiveness. IGF-1 LR3 plays a vital role in stimulating cell division, proliferation, and intercellular communication. Its unique properties improve fat metabolism, muscle repair, and hypertrophy, particularly through the inhibition of myostatin. Recent studies have also indicated its potential benefits for enhancing lactation in nursing mothers. The structural modifications of IGF-1 LR3 consist of adding 13 amino acids to the N-terminal end of IGF-1 and replacing the glutamic acid at position 3 with an arginine residue.

What Are the Effects of IGF-1 LR3?

IGF-1 LR3 (insulin-like growth factor-1 long arginine 3) is a synthetic derivative of IGF-1, engineered to amplify its physiological effects. The peptide’s extended half-life and unique structure allow it to remain active in circulation, significantly enhancing its biological activity.

• Cell Division and Growth:
  IGF-1 LR3 is a powerful promoter of cell division and proliferation, playing an essential role in regulating the growth and development of various tissues. This contributes to overall body growth and maintenance.
• Muscle Repair and Hypertrophy:
  A standout feature of IGF-1 LR3 is its ability to facilitate muscle repair and hypertrophy. It achieves this by inhibiting myostatin, a protein that negatively regulates muscle growth. By reducing myostatin’s inhibitory effects, IGF-1 LR3 promotes muscle tissue recovery and supports the development of increased muscle mass.
• Fat Metabolism:
  IGF-1 LR3 is instrumental in metabolic regulation, particularly in enhancing fat metabolism. This property makes it relevant for weight management and fat loss, as it may promote the breakdown and utilization of stored fat for energy.
• Improved Lactation:
  Emerging studies suggest that IGF-1 LR3 may improve lactation, particularly in mothers with young children. Its effects on cellular processes might enhance mammary gland function, thereby supporting milk production.
• Cell-to-Cell Communication:
  Like other IGF-1 derivatives, IGF-1 LR3 plays a significant role in cell-to-cell communication. It is involved in signaling pathways that govern crucial cellular activities, including growth, differentiation, and survival.

While these effects underscore the diverse applications of IGF-1 LR3, ongoing research continues to explore its potential uses in fields such as sports science, endocrinology, and lactation. As with any peptide, its administration and effects should be approached with careful study and monitoring to evaluate both risks and benefits.

PRODUCTS ARE FOR RESEARCH PURPOSES ONLY